HEROIC - Integrating knowledge across human and environmental risk assessment
Description
pulled from site's meta descriptionThe objectives of HEROIC are: to develop a framework for integrated methodologies and approaches for human and environmental risk assessment (HRA&ERA) for all groups of chemicals, with specific focus on mixtures, exploring how data generated in ecotoxicology and human toxicology can be applied across them to facilitate a close co-operation between the bodies involved in RA to improve the quality, communication, added value and recognition of RA, thereby helping the improvement of risk management decisions to involve all the relevant stakeholders in the RA value chain across the EU, making them contribute to the harmonization of the approaches
Domain Resolution
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- AboutUs AutoGen
- HEROIC - Health and Environmental Risks: Organisation
- Integration and Cross-fertilisation of Scientific Knowledge.
- Integrating knowledge across human and environmental risk assessment
- Risk assessment
- Human risk assessment
- Environmental risk assessment
- Integrated risk assessment
- Toxicology
- Ecotoxicology
- ERA
- HRA
- IRA
- Hazard
- Exposure
- Endpoint
- Data requirement
- Pharmaceutical
- Biocide
- Pesticide
- plant protection product
- Chemical
- Food additive
- Cosmetics
- Mixture
- Mode of action
- MoA
- Case study
- case studies
- Regulatory agency
- stakeholder
- expert
- end user
- end-user
- database
- training
- e-learning
- alternative testing
- QSAR
- ITS
- Extrapolation
- Read-across
- Chemical Regulation
- REACH Regulation
- Integrated Testing Strategies
- Quantitative Structure Activity Relationships
- PBPK
- multi-media models
- transport
- fate
- degradation
- biodisponibility
- 3R’s strategy
- EU
- non-test methods
- test methods
- In vivo
- In vitro
- In silico
- Species specificity
- Variability
- Reliability
- Weight of evidence
- Ranking
- Uncertainty
- Endpoint similarity
- Species homology
- Adverse Outcome Pathways (AOP)
- Guideline
- guidance
- Lines of Evidence (LoE)
- computational methods
- Biokinetic models
- thresholds of toxicological concern
- exposure-based waiving
- modelling
- Regulatory toxicology
- Regulatory frameworks
- Regulatory procedures
- regulatory requirements